THE CASE FOR CHANGE

End Animal Testing

200 million animals suffer in laboratories every year. 95% of drugs deemed safe in animals fail
in human trials. The science is broken — and we have the solutions.

Take Action
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Animals suffer in labs

every single year globally

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Drug failure rate

post animal testing in humans

90–93%

Primate DNA similarity

yet still fails to predict humans

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Regulatory requirement

for animal tests in many EU categories

THE EVIDENCE

Why Animal Testing Fails Humans

Poor Predictability

The NIH reports that 95% of drugs safe and effective in animals fail in human clinical trials. Only 5% of animal-tested therapies gain human approval.

Species Biology Differs

Rodents have fundamentally different immune systems, metabolic processes and disease mechanisms to humans — making results species-specific, not universal.

Human Genetic Diversity Ignored

Animal models cannot represent the genetic variation in human populations affecting treatment responses, metabolism and disease vulnerability.

Ethically Indefensible

With validated, accurate human-relevant alternatives available, the continued use of animals for research is both scientifically unjustifiable and ethically wrong.

REAL CASES

When Animal Data Gets It Wrong

Aspirin

Safe for humans

Harmed animals in testing — but became one of the most used medicines in human history.

Penicillin

Safe for humans

Lethal to guinea pigs — yet saves millions of human lives every year.

Thalidomide

Harmful to humans

Deemed safe in rodents — caused severe birth defects in 10,000+ human infants.

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Support our campaigns, share our resources, and help us hold governments and institutions
accountable for ending animal testing.

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